The Appin Massacre is one of the darkest days in Macarthur’s history.
It's estimated at least 14 Dharawal men, women and children died in the colonial massacre.
Only two women and three children survived according to the account of Captain James Wallis, who led the attack.
The event will be commemorated at two ceremonies this month.
On Sunday, April 14 a ceremony will be conducted at Cataract Dam, near the site of the massacre, while on Wednesday, April 17 a flag raising memorial will take place in the forecourt of the Campbelltown Council civic building.
Campbelltown mayor George Brticevic said the massacre had a significant and lasting impact.
"It is important we remember the Appin Massacre, both for the tragedy of the lives lost and to ensure that the gravity of this event, and others like it, is properly understood," he said.
"People living in Campbelltown and throughout the country need to know injustices that have occurred in the past will not be written off as historic footnotes."
The Winga Myamly Reconciliation Group and the Aboriginal Communities of Macarthur will host the memorial service at 11am to 3.30pm on Sunday, April 14 at the Cataract Dam picnic area.
There will be a BBQ at midday followed by the official ceremony at 1pm.
For more information about the services, visit: campbelltown.nsw.com.au.